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Effects of Peach (Prunus persica)-Derived Glucosylceramide

Methods: Three separate experiments were performed: evaluations of the effect of peach-derived glucosylceramide application on the ceramide content in a three-dimensional hu-man cultured skin model, water retention effect of the oral administration of the peach-derived glucosylceramide on human skin functionality, and safety of the long-term admin-istration of …

N. Korea's parliamentary session

Sep 30, 2021 · N. Korea's parliamentary session. This photo, released by North Korea's official Korean Central News Agency on Sept. 30, 2021, shows Kim Yo-jong, North Korean leader Kim Jong-un's sister and currently vice department director of the ruling Workers' Party's Central Committee, who was elected as a member of the State Affairs Commission, the country's …

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Measurement and Estimation of GFR in Children and

Nov 01, 2009 · GFR is the best indicator of renal function in children and adolescents and is critical for diagnosing acute and chronic kidney impairment, intervening early to prevent end-stage renal failure, prescribing nephrotoxic drugs and drugs cleared by a failing kidney, and monitoring for side effects of medications. Renal inulin clearance was the gold standard for GFR but is …

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Discovery and engineering of colchicine alkaloid

Jul 22, 2020 · Discovery of a near-complete colchicine biosynthetic pathway enables the engineered production of the tropolone-containing alkaloid N-formyldemecolcine from amino acid precursors in Nicotiana ...

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Inhibition of CYP3A4 enhances aloe-emodin induced

1. Introduction. Aloe-emodin (AE) is a natural hydroxyanthraquinone derivative that was found in many widely-used ethnic medicines, such as Senna alata (L.) Roxb.Rheum palmatum L., Aloe vera, and Polygonum multiflorum Thunb. (Kline et al., 2017; Yang et al., 2019; Dong et al., 2020).Studies have shown that AE has a variety of pharmacological effects, including anticancer, antifungal, …

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Reconstitution of a 10-gene pathway for synthesis of the

Feb 11, 2014 · Alkaloids were separated by reverse-phase HPLC (Perkin Elmer SERIES 200 Micropump, Perkin Elmer, Norfolk, CT, USA) using an Agilent Zorbax Rapid Resolution HT C18 2.1*30 mm, 1.8 micron column.

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